SCHEMBL851485

SCHEMBL851485

Cl[Zr](=C(c1ccccc1)c1ccccc1)(c1cccc2c1Cc1ccccc1-2)C1c2ccccc2-c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.35
SRD5A2 P31213 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HTR7 P34969 1/20 0.32
HTR2B P41595 1/20 0.32
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL618217 0.71 PNMT (0.49) PNMTSRD5A2NPC1RAB9AHTR7
SCHEMBL3384917 0.71 PNMT (0.49) PNMTSRD5A2NPC1RAB9AHTR7
SCHEMBL3683305 0.70 NPC1 (0.37) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7130890 0.69 PNMT (0.32) PNMTNPC1RAB9A
SCHEMBL7265200 0.68 PNMT (0.35) PNMTNPC1RAB9A
SCHEMBL8755327 0.67 PNMT (0.47) PNMTSRD5A2NPC1RAB9AHTR7
SCHEMBL673541 0.66 PNMT (0.35) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7272264 0.66 PNMT (0.35) PNMTNPC1RAB9AHTR7HTR2B
Hydrochloric Acid SCHEMBL6558556 0.66 PNMT (0.46) PNMTSRD5A2NPC1RAB9AHTR7
SCHEMBL7643272 0.65 PNMT (0.42) PNMTSRD5A2NPC1RAB9AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1629973-B1 Laminate TOSOH CORP (JP) 2012-03-28 EP disclosed
US-7544422-B2 Laminate TOSOH CORPORATION (JP) 2009-06-09 US disclosed
EP-1642926-B1 Non-crosslinked polyethylene foam TOSOH CORP (JP) 2007-06-20 EP disclosed
EP-1642926-A1 Non-crosslinked polyethylene foam Tosoh Corporation (JP) 2006-04-05 EP disclosed
US-20060069173-A1 Non-crosslinked polyethylene foam TOSOH CORPORATION 2006-03-30 US disclosed
EP-1629973-A1 Laminate Tosoh Corporation (JP) 2006-03-01 EP disclosed
US-20060024519-A1 Laminate TOSOH CORPORATION 2006-02-02 US disclosed