Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670854 | 0.81 | FDFT1 (0.42) | POLBALDH1A1CHRNB2CHRNA4MAPT | |
| SCHEMBL15544585 | 0.80 | POLB (0.46) | POLBALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL3567993 | 0.78 | KDM4E (0.43) | POLBALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL4240888 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTNPC1MAPK1HTT | |
| SCHEMBL14060623 | 0.75 | POLB (0.47) | POLBPABPC1ALDH1A1MAPTNPC1 | |
| SCHEMBL16219449 | 0.74 | POLB (0.42) | POLBPABPC1ALDH1A1MAPTNPC1 | |
| SCHEMBL34471244 | 0.74 | MAPK1 (0.46) | MAPK1FDFT1FPR2 | |
| SCHEMBL16219445 | 0.73 | CARM1 (0.54) | POLBALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL25395289 | 0.71 | CHRNB2 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL30555442 | 0.71 | CHRNB2 (0.45) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643311-A1 | BICYCLIC GPR119 MODULATORS | Lupin Limited (IN) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |