⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15237122 | 0.73 | — | — | |
| SCHEMBL49879 | 0.73 | — | — | |
| SCHEMBL360856 | 0.73 | — | — | |
| Iodide SCHEMBL29215238 | 0.71 | — | — | |
| SCHEMBL1357902 | 0.71 | LMNA (0.44) | — | |
| SCHEMBL16478014 | 0.70 | CYP2C9 (0.42) | — | |
| SCHEMBL598089 | 0.69 | — | — | |
| SCHEMBL16579815 | 0.69 | — | — | |
| SCHEMBL6422381 | 0.69 | — | — | |
| SCHEMBL24565205 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190209713-A1 | CEST SYSTEMS EXHIBITING A CONCENTRATION INDEPENDENT RESPONSIVENESS | BRACCO IMAGING S.P.A. (IT) | 2019-07-11 | — | — | US | disclosed |
| US-10328162-B1 | CEST systems exhibiting a concentration independent responsiveness | BRACCO IMAGING S.P.A. (IT) | 2019-06-25 | — | — | US | disclosed |
| US-10232060-B2 | CEST systems exhibiting a concentration independent responsiveness | BRACCO IMAGING S.P.A. (IT) | 2019-03-19 | — | — | US | disclosed |
| EP-2635311-B1 | CEST SYSTEMS EXHIBITING A CONCENTRATION INDEPENDENT RESPONSIVENESS | BRACCO IMAGING SPA (IT) | 2017-08-16 | — | — | EP | disclosed |
| WO-2016168471-A1 | DUAL DISULFIDE DRUG CONJUGATES | ENDOCYTE, INC. (US) | 2016-10-20 | — | — | WO | disclosed |
| WO-2016089879-A1 | CONJUGATES OF GARFTASE INHIBITORS | ENDOCYTE, INC. (US) | 2016-06-09 | — | — | WO | disclosed |
| US-20130195768-A1 | CEST SYSTEMS EXHIBITING A CONCENTRATION INDEPENDENT RESPONSIVENESS | BRACCO IMAGING S.P.A. (IT) | 2013-08-01 | — | — | US | disclosed |
| EP-2457594-A1 | Cest systems exhibiting a concentration independent responsiveness | Bracco Imaging S.p.A (IT) | 2012-05-30 | — | — | EP | disclosed |