SCHEMBL1357902

SCHEMBL1357902

OCC(O)COC(O)CO

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
ALDH1A1 P00352 1/20 0.44
USP2 O75604 1/20 0.37
THRB P10828 1/20 0.36
CYP1A2 P05177 3/20 0.33
KDM4E B2RXH2 3/20 0.33
AGTR1 P30556 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
DUSP3 P51452 1/20 0.32
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1619852 0.83 LMNA (0.40) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL285035 0.83 THRB (0.52) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL20646684 0.82 USP2 (0.36) LMNAALDH1A1USP2
SCHEMBL3739869 0.81 USP2 (0.42) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL1671352 0.81 LMNA (0.38) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL888322 0.81 TSHR (0.43) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL8991618 0.79
SCHEMBL15023217 0.78 USP2 (0.35) LMNAALDH1A1USP2CYP1A2KDM4E
SCHEMBL1206579 0.78 USP2 (0.44) LMNAALDH1A1USP2THRBCYP1A2
SCHEMBL28951126 0.78 ALDH1A1 (0.35) LMNAALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110288230-A1 METHOD FOR PREPARING POLYHYDROXY-URETHANES RHODIA OPERATIONS (FR) 2011-11-24 US claimed
CN-105431139-B For carrying out the stereospecificity lipid of local treatment with the stimulation-sensibility nano-carrier system recycled for a long time 特默佐梅有限公司 2019-10-01 CN disclosed
CN-105431139-A Stereospecific lipids for locoregional therapy with long-term circulating stimuli-sensitive nanocarrier systems THERMOSOME GmbH 2016-03-23 CN disclosed
EP-2262752-B1 IMPROVED HYDROGENATION PROCESS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-19 EP disclosed
US-8324434-B2 Hydrogenation process DOW GLOBAL TECHNOLOGIES, LLC (US) 2012-12-04 US disclosed
US-20110288230-A1 METHOD FOR PREPARING POLYHYDROXY-URETHANES RHODIA OPERATIONS (FR) 2011-11-24 US disclosed
US-8017719-B2 Method for preparing polyhydroxy-urethanes RHODIA OPERATIONS (FR) 2011-09-13 US disclosed
US-20110060168-A1 IMPROVED HYDROGENATION PROCESS DOW GLOBAL TECHNOLOGIES LLC 2011-03-10 US disclosed
EP-2262752-A1 IMPROVED HYDROGENATION PROCESS Dow Global Technologies Inc. (US) 2010-12-22 EP disclosed
WO-2009111352-A1 IMPROVED HYDROGENATION PROCESS DOW GLOBAL TECHNOLOGIES, INC. (US) 2009-09-11 WO disclosed
EP-0423266-A4 METHOD AND COMPOSITION FOR TREATMENT OF PERIODONTAL DISEASE 1991-09-25 EP disclosed
EP-0423266-A1 METHOD AND COMPOSITION FOR TREATMENT OF PERIODONTAL DISEASE BENHURI, Marc N (US) 1991-04-24 EP disclosed
WO-1990009779-A1 METHOD AND COMPOSITION FOR TREATMENT OF PERIODONTAL DISEASE BENHURI MARC N (US) 1990-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288230-A1 METHOD FOR PREPARING POLYHYDROXY-URETHANES UROD, HPD, ALKBH3 LMNA 2578/4885ALDH1A1 2408/4885USP2 161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.