Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 7/20 | 0.44 |
| ▸ | KDM1A | O60341 | 6/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19511303 | 0.89 | FFAR4 (0.37) | EP300KDM1APIM1PIM2 | |
| SCHEMBL21747529 | 0.82 | CCNK (0.40) | PIM1PIM2 | |
| SCHEMBL8511650 | 0.76 | IKBKB (0.40) | SLC6A2SLC6A3IKBKBCHUK | |
| SCHEMBL28700076 | 0.76 | ARNT (0.30) | — | |
| SCHEMBL8511906 | 0.75 | FFAR4 (0.44) | PIM1PIM2 | |
| SCHEMBL1103830 | 0.69 | EP300 (0.56) | EP300KDM1ATDP1 | |
| SCHEMBL20758267 | 0.68 | TDP1 (0.56) | EP300KDM1ASLC6A2SLC6A4HTR3A | |
| Hydrochloric Acid SCHEMBL16757775 | 0.68 | EP300 (0.54) | EP300KDM1ATDP1 | |
| SCHEMBL743307 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL16757756 | 0.67 | TDP1 (0.59) | EP300KDM1ASLC6A2SLC6A4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643311-A1 | BICYCLIC GPR119 MODULATORS | Lupin Limited (IN) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |