Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.40 |
| ▸ | CHUK | O15111 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19510937 | 0.84 | FFAR4 (0.36) | — | |
| SCHEMBL25145928 | 0.76 | PLAT (0.38) | IKBKBCHUKHRH1CTSLCTSB | |
| SCHEMBL8515315 | 0.76 | EP300 (0.44) | IKBKBCHUKSLC6A2SLC6A3 | |
| SCHEMBL8513265 | 0.74 | HRH3 (0.33) | — | |
| SCHEMBL8515255 | 0.73 | FFAR4 (0.38) | IKBKBCHUK | |
| SCHEMBL21746144 | 0.71 | HRH1 (0.41) | IKBKBCHUKHRH1ROCK1HTR1A | |
| SCHEMBL6179188 | 0.70 | HRH1 (0.43) | IKBKBCHUKHRH1ROCK1HTR1A | |
| SCHEMBL23702894 | 0.68 | CHRNB2 (0.38) | HTR1ASLC6A2 | |
| SCHEMBL23702898 | 0.68 | CHRNB2 (0.38) | HTR1ASLC6A2 | |
| SCHEMBL2591565 | 0.67 | ACACB (0.53) | IKBKBCHUKHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643311-A1 | BICYCLIC GPR119 MODULATORS | Lupin Limited (IN) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |