Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.62 |
| ▸ | CA1 | P00915 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 3/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30767880 | 0.87 | CA9 (0.59) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL3250182 | 0.87 | CA9 (0.59) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL17358708 | 0.81 | CA9 (0.64) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL8388797 | 0.80 | CA9 (0.66) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL4929370 | 0.79 | CA9 (0.61) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL11180486 | 0.78 | CA9 (0.64) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL4609492 | 0.78 | KDM4E (0.61) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL3245747 | 0.78 | CA9 (0.56) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL483004 | 0.77 | KDM4E (0.61) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL29403594 | 0.77 | KDM4E (0.61) | CA9CA1CA2CA5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012070024-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2012-05-31 | — | — | WO | disclosed |