Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | HPGD | P15428 | 9/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.58 |
| ▸ | GLA | P06280 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 3/20 | 0.58 |
| ▸ | CASP7 | P55210 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3250182 | 1.00 | CA9 (0.59) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL8515319 | 0.87 | CA9 (0.62) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL15924043 | 0.86 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL4609492 | 0.85 | KDM4E (0.61) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL1362612 | 0.83 | ALDH1A1 (0.62) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL17358708 | 0.83 | CA9 (0.64) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL31710481 | 0.83 | KCNA3 (0.52) | CA9ALDH1A1KDM4EHPGDCA12 | |
| SCHEMBL27780809 | 0.82 | AKR1B1 (0.49) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL10709372 | 0.82 | ALDH1A1 (0.61) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL4609859 | 0.81 | ALDH1A1 (0.60) | CA9CA1CA2CA5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4316495-A1 | NUCLEIC ACID MOLECULE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE | Aptacure Therapeutics Limited (HK) | 2024-02-07 | — | — | EP | claimed |
| CN-122094697-A | Aptamer conjugates for targeted degradation of osteopetron | — | 2026-05-26 | — | — | CN | disclosed |
| CN-117916377-A | Aptamer for DKK1 and use thereof | 安沛治疗有限公司 | 2024-04-19 | — | — | CN | disclosed |
| EP-4316495-A1 | NUCLEIC ACID MOLECULE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE | Aptacure Therapeutics Limited (HK) | 2024-02-07 | — | — | EP | disclosed |