Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.72 |
| ▸ | HTT | P42858 | 4/20 | 0.72 |
| ▸ | EGFR | P00533 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | APP | P05067 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALPG | P10696 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497590 | 0.84 | APP (1.00) | MAPK1HTTEGFRLMNAAPP | |
| SCHEMBL23202914 | 0.82 | HTT (0.78) | MAPK1HTTEGFRLMNAAPP | |
| SCHEMBL8543175 | 0.82 | HTT (0.83) | MAPK1HTTEGFRLMNAAPP | |
| SCHEMBL30827884 | 0.82 | HTT (0.78) | MAPK1HTTEGFRLMNAAPP | |
| SCHEMBL8483329 | 0.82 | HTT (0.64) | MAPK1HTTEGFRLMNAAPP | |
| SCHEMBL8482467 | 0.82 | HTT (0.72) | MAPK1HTTEGFRLMNAAPP | |
| SCHEMBL8504069 | 0.82 | HTT (0.72) | MAPK1HTTEGFRLMNAAPP | |
| SCHEMBL17803673 | 0.81 | HTT (0.81) | MAPK1HTTEGFRLMNAAPP | |
| SCHEMBL9608046 | 0.79 | GAA (0.55) | MAPK1HTTEGFRLMNAAPP | |
| SCHEMBL8543007 | 0.79 | HTT (0.77) | MAPK1HTTEGFRLMNAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |