Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.77 |
| ▸ | EGFR | P00533 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | APP | P05067 | 2/20 | 0.77 |
| ▸ | AURKA | O14965 | 1/20 | 0.63 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | TEK | Q02763 | 1/20 | 0.61 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GALR3 | O60755 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CCNC | P24863 | 1/20 | 0.53 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.53 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548572 | 0.89 | EGFR (0.71) | HTTEGFRLMNAMAPK1APP | |
| SCHEMBL15684945 | 0.88 | HTT (0.63) | HTTEGFRLMNAMAPK1APP | |
| SCHEMBL8497590 | 0.87 | APP (1.00) | HTTEGFRLMNAMAPK1APP | |
| SCHEMBL8548720 | 0.87 | HTT (0.69) | HTTEGFRLMNAMAPK1APP | |
| SCHEMBL157421 | 0.86 | NFKB1 (0.63) | HTTEGFRLMNAMAPK1APP | |
| SCHEMBL29350229 | 0.86 | NFKB1 (0.63) | HTTEGFRLMNAMAPK1APP | |
| SCHEMBL8543175 | 0.85 | HTT (0.83) | HTTEGFRLMNAMAPK1APP | |
| SCHEMBL8483825 | 0.84 | HTT (0.67) | HTTEGFRLMNAMAPK1APP | |
| SCHEMBL8542891 | 0.83 | HTT (0.54) | HTTEGFRLMNAMAPK1APP | |
| SCHEMBL9387280 | 0.83 | HTT (0.66) | HTTEGFRLMNAMAPK1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |