Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 8/20 | 0.72 |
| ▸ | EGFR | P00533 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | APP | P05067 | 2/20 | 0.72 |
| ▸ | LDHA | P00338 | 1/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | NR2F2 | P24468 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GALR3 | O60755 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483825 | 0.86 | HTT (0.67) | HTTEGFRMAPK1LMNAAPP | |
| SCHEMBL8497590 | 0.84 | APP (1.00) | HTTEGFRMAPK1LMNAAPP | |
| SCHEMBL8543175 | 0.82 | HTT (0.83) | HTTEGFRMAPK1LMNAAPP | |
| SCHEMBL23202914 | 0.82 | HTT (0.78) | HTTEGFRMAPK1LMNAAPP | |
| SCHEMBL30827884 | 0.82 | HTT (0.78) | HTTEGFRMAPK1LMNAAPP | |
| SCHEMBL9608031 | 0.82 | LDHA (0.57) | HTTEGFRMAPK1LMNAAPP | |
| SCHEMBL8543007 | 0.82 | HTT (0.77) | HTTEGFRMAPK1LMNAAPP | |
| SCHEMBL8504069 | 0.82 | HTT (0.72) | HTTEGFRMAPK1LMNAAPP | |
| SCHEMBL8515907 | 0.82 | MAPK1 (0.72) | HTTEGFRMAPK1LMNAAPP | |
| SCHEMBL17001434 | 0.81 | APP (1.00) | HTTEGFRMAPK1LMNAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011007839-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | 株式会社エス・ディー・エス バイオテック (JP) | 2011-01-20 | — | — | WO | disclosed |