Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800268 | 0.79 | EPHX2 (0.48) | EPHX2KMT2ACASP3CHRM3 | |
| SCHEMBL29872137 | 0.79 | EPHX2 (0.48) | EPHX2KMT2ACASP3CHRM3 | |
| SCHEMBL28747376 | 0.78 | NPC1 (0.56) | CASP3 | |
| Acetic Acid SCHEMBL1157575 | 0.76 | CHRM3 (0.58) | EPHX2KMT2ACHRM3 | |
| SCHEMBL9588677 | 0.75 | EPHX2 (0.56) | EPHX2KMT2ACASP3CHRM3 | |
| SCHEMBL3234085 | 0.74 | KMT2A (0.58) | EPHX2KMT2ACASP3CHRM3 | |
| SCHEMBL29067330 | 0.74 | EPHX2 (0.57) | EPHX2KMT2ACHRM3 | |
| SCHEMBL119223 | 0.73 | EPHX2 (0.60) | EPHX2KMT2ACASP3CHRM3 | |
| SCHEMBL29401765 | 0.73 | EPHX2 (0.60) | EPHX2KMT2ACASP3CHRM3 | |
| SCHEMBL29913938 | 0.73 | EPHX2 (0.60) | EPHX2KMT2ACASP3CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457896-A1 | Tripeptides as caspase modulators | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2457895-A1 | Tetrapeptide analogs | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |