Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728300 | 0.94 | CA2 (0.40) | CA2CA4S1PR2S1PR4S1PR1 | |
| SCHEMBL8729461 | 0.87 | CA2 (0.42) | CA2CA4LMNABLMALDH1A1 | |
| SCHEMBL8634866 | 0.80 | GPR84 (0.38) | TDP1 | |
| SCHEMBL2692733 | 0.79 | GPR84 (0.44) | ALDH1A1TDP1 | |
| SCHEMBL28308288 | 0.78 | GPR84 (0.34) | TDP1 | |
| SCHEMBL8424379 | 0.76 | CAMK2A (0.33) | LMNAALDH1A1 | |
| SCHEMBL7747031 | 0.76 | CA2 (0.44) | CA2CA4LMNABLMTDP1 | |
| SCHEMBL1880686 | 0.76 | CAMK2A (0.33) | LMNAALDH1A1 | |
| SCHEMBL6578196 | 0.73 | TYMS (0.34) | CA2CA4S1PR2S1PR4S1PR1 | |
| SCHEMBL4553554 | 0.72 | GABRR1 (0.32) | CA2CA4LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929198-A | HIGH MOLECULAR WEIGHT POLYMERS MODIFIED WITH N-DERIVATIZED COMPOUNDS | NALCO CHEMICAL COMPANY (US) | 1999-07-27 | — | — | US | claimed |
| EP-0832851-A1 | Biodegradable poly (amino acids), derivatized amino acid polymers and methods for making the same | Nalco Chemical Company (US) | 1998-04-01 | — | — | EP | claimed |