Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | APP | P05067 | 2/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | AURKA | O14965 | 2/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497432 | 0.83 | RAB9A (0.67) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL19118217 | 0.82 | CDK1 (1.00) | CDK1HTTCNR1CNR2 | |
| SCHEMBL9608029 | 0.81 | CDK1 (0.55) | CDK1HTTLMNAAPPEGFR | |
| SCHEMBL8497590 | 0.80 | APP (1.00) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL13399982 | 0.79 | AURKA (1.00) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL23202914 | 0.78 | HTT (0.78) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL8543175 | 0.78 | HTT (0.83) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL30827884 | 0.78 | HTT (0.78) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL8482467 | 0.78 | HTT (0.72) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL8504069 | 0.78 | HTT (0.72) | HTTLMNAAPPEGFRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |