Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 2/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8516666 | 0.97 | USP2 (0.38) | USP2MEN1KMT2ALMNACYP1A2 | |
| Trifluoroacetic Acid SCHEMBL8516518 | 0.92 | USP2 (0.37) | USP2MEN1KMT2ALMNACYP1A2 | |
| Trifluoroacetic Acid SCHEMBL8365255 | 0.91 | MEN1 (0.42) | USP2MEN1KMT2ACYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8516825 | 0.91 | CA12 (0.40) | USP2MEN1KMT2ALMNACYP1A2 | |
| Trifluoroacetic Acid SCHEMBL8516685 | 0.90 | MEN1 (0.40) | USP2MEN1KMT2ALMNACYP1A2 | |
| Trifluoroacetic Acid SCHEMBL8516860 | 0.88 | MEN1 (0.41) | USP2MEN1KMT2ACYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8368543 | 0.87 | CFTR (0.42) | USP2MEN1KMT2ACYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8367895 | 0.86 | PTGDR2 (0.36) | USP2MEN1KMT2ALMNATP53 | |
| Trifluoroacetic Acid SCHEMBL8516655 | 0.85 | TP53 (0.36) | USP2MEN1KMT2ALMNATP53 | |
| Trifluoroacetic Acid SCHEMBL8516818 | 0.84 | CFTR (0.42) | USP2MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |