Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8368691 | 0.91 | TP53 (0.39) | TP53PDE4BPDE4DPTGDR2KMT2A | |
| Trifluoroacetic Acid SCHEMBL8365308 | 0.87 | CFTR (0.40) | TP53PDE4BPDE4DPTGDR2KMT2A | |
| Trifluoroacetic Acid SCHEMBL8516078 | 0.85 | USP2 (0.39) | TP53PDE4BPDE4DPTGDR2KMT2A | |
| Trifluoroacetic Acid SCHEMBL8367895 | 0.84 | PTGDR2 (0.36) | TP53PDE4BPDE4DPTGDR2KMT2A | |
| Trifluoroacetic Acid SCHEMBL8516666 | 0.84 | USP2 (0.38) | TP53PDE4BPDE4DPTGDR2KMT2A | |
| Trifluoroacetic Acid SCHEMBL8516685 | 0.83 | MEN1 (0.40) | TP53PDE4BPDE4DPTGDR2KMT2A | |
| Trifluoroacetic Acid SCHEMBL8516518 | 0.83 | USP2 (0.37) | TP53PDE4BPDE4DPTGDR2KMT2A | |
| Trifluoroacetic Acid SCHEMBL8367899 | 0.83 | LMNA (0.44) | PDE4BPDE4DKMT2AMEN1USP2 | |
| SCHEMBL8516657 | 0.82 | PDE4B (0.32) | PDE4BPDE4DPOLB | |
| Trifluoroacetic Acid SCHEMBL8516758 | 0.81 | PTGDR2 (0.39) | TP53PDE4BPDE4DPTGDR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |