Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8368543 | 0.97 | CFTR (0.42) | CFTRMEN1KMT2AUSP2ACSS2 | |
| Trifluoroacetic Acid SCHEMBL8516660 | 0.92 | CFTR (0.46) | CFTRUSP2ACSS2TLR8TLR7 | |
| Trifluoroacetic Acid SCHEMBL8517280 | 0.91 | CFTR (0.41) | CFTRMEN1KMT2AUSP2ACSS2 | |
| Trifluoroacetic Acid SCHEMBL8362794 | 0.90 | CFTR (0.42) | CFTRMEN1KMT2AUSP2ACSS2 | |
| Trifluoroacetic Acid SCHEMBL8516860 | 0.90 | MEN1 (0.41) | MEN1KMT2AUSP2MAPK1KDM4E | |
| Trifluoroacetic Acid SCHEMBL8516150 | 0.89 | CFTR (0.47) | CFTRUSP2ACSS2TLR8CA12 | |
| Trifluoroacetic Acid SCHEMBL8516666 | 0.87 | USP2 (0.38) | MEN1KMT2AUSP2TP53ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8365255 | 0.86 | MEN1 (0.42) | MEN1KMT2AUSP2MAPK1KDM4E | |
| Trifluoroacetic Acid SCHEMBL8365308 | 0.86 | CFTR (0.40) | CFTRMEN1KMT2AUSP2ACSS2 | |
| Trifluoroacetic Acid SCHEMBL8365276 | 0.85 | CFTR (0.41) | CFTRMEN1KMT2AUSP2ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |