Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491180 | 0.89 | LDHA (0.59) | LDHAHTTLMNAEGFRMAPK1 | |
| SCHEMBL8516140 | 0.82 | HTT (0.54) | LDHAHTTLMNAEGFRMAPK1 | |
| SCHEMBL8483285 | 0.80 | APP (0.68) | LDHAHTTLMNAEGFRMAPK1 | |
| SCHEMBL9609184 | 0.80 | LMNA (0.56) | LDHAHTTLMNAEGFRMAPK1 | |
| SCHEMBL8483419 | 0.79 | HTT (0.60) | LDHAHTTLMNAEGFRMAPK1 | |
| SCHEMBL9608032 | 0.79 | LDHA (0.52) | LDHAHTTLMNAEGFRMAPK1 | |
| SCHEMBL8490469 | 0.78 | HTT (0.54) | LDHAHTTLMNAEGFRMAPK1 | |
| SCHEMBL8483442 | 0.77 | HTT (0.67) | LDHAHTTLMNAEGFRMAPK1 | |
| SCHEMBL9609092 | 0.76 | LMNA (0.65) | LDHAHTTLMNAEGFRMAPK1 | |
| SCHEMBL8497243 | 0.76 | HTT (0.65) | LDHAHTTLMNAEGFRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011007839-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | 株式会社エス・ディー・エス バイオテック (JP) | 2011-01-20 | — | — | WO | disclosed |