Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2710984 | 1.00 | GRIN1 (0.37) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL4058303 | 0.86 | GRIN2D (0.32) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL5000910 | 0.84 | EPHX2 (0.40) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL8515530 | 0.81 | — | — | |
| SCHEMBL2187126 | 0.80 | PGR (0.33) | PGR | |
| SCHEMBL2708058 | 0.79 | EPHX2 (0.36) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL2191037 | 0.77 | PGR (0.31) | PGR | |
| SCHEMBL2763490 | 0.77 | PGR (0.33) | PGR | |
| SCHEMBL2188665 | 0.77 | — | — | |
| SCHEMBL6392406 | 0.76 | PGR (0.47) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142879-A1 | COMPOSITION FOR FILM FORMATION, INSULATING FILM AND SEMICONDUCTOR DEVICE | SUMITOMO BAKELITE COMPANY LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2457932-A1 | COMPOSITION FOR FILM FORMATION, INSULATING FILM, AND SEMICONDUCTOR DEVICE | Sumitomo Bakelite Company Limited (JP) | 2012-05-30 | — | — | EP | disclosed |