SCHEMBL31308

SCHEMBL31308

CCCCCN1CCOC1=O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.51
KDM4E B2RXH2 1/20 0.45
PIK3CD O00329 1/20 0.41
NR1H2 P55055 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
GBA1 P04062 1/20 0.39
ALOX5 P09917 2/20 0.38
NQO2 P16083 1/20 0.37
PTGS1 P23219 3/20 0.37
PTGS2 P35354 3/20 0.37
MGLL Q99685 3/20 0.37
FAAH O00519 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27992732 0.98 NAAA (0.54) NAAAKDM4EPIK3CDNR1H2ALDH1A1
SCHEMBL9250191 0.98 NAAA (0.54) NAAAKDM4EPIK3CDNR1H2ALDH1A1
Hydrogen Sulfide SCHEMBL28268418 0.98 NAAA (0.50) NAAAKDM4EPIK3CDNR1H2ALDH1A1
SCHEMBL419534 0.98 NAAA (0.54) NAAAKDM4EPIK3CDNR1H2ALDH1A1
SCHEMBL8512828 0.98 NAAA (0.54) NAAAKDM4EPIK3CDNR1H2ALDH1A1
SCHEMBL14184720 0.98 NAAA (0.54) NAAAKDM4EPIK3CDNR1H2ALDH1A1
SCHEMBL4860823 0.98 NAAA (0.54) NAAAKDM4EPIK3CDNR1H2ALDH1A1
SCHEMBL4573839 0.94 NAAA (0.49) NAAAKDM4EPIK3CDNR1H2ALDH1A1
SCHEMBL8516440 0.89 PIK3CD (0.54) NAAAKDM4EPIK3CDALDH1A1GAA
Pyrrolidine SCHEMBL7380973 0.89 NAAA (0.43) NAAAKDM4EPIK3CDNR1H2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1853 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117718080-A Method for synthesizing aryl oxazolidone catalyst 沈阳化工大学 2024-03-19 CN claimed
US-11203005-B2 Method for producing water-absorbing polymer particles by suspension polymerization BASF SE (DE) 2021-12-21 US claimed
EP-3473655-B1 METHOD FOR PRODUCING WATER-ABSORBENT POLYMER PARTICLES BY SUSPENSION POLYMERISATION BASF SE (DE) 2021-06-09 EP claimed
CN-107207635-B Method for producing water-absorbing polymer particles by suspension polymerization 巴斯夫欧洲公司 2020-12-04 CN claimed
EP-3473655-A1 METHOD FOR PRODUCING WATER-ABSORBENT POLYMER PARTICLES BY SUSPENSION POLYMERISATION BASF SE (DE) 2019-04-24 EP claimed
US-10208170-B2 Process for producing surface-postcrosslinked water-absorbent polymer particles BASF SE (DE) 2019-02-19 US claimed
EP-3262089-B1 A PROCESS FOR PRODUCING SURFACE-POSTCROSSLINKED WATER-ABSORBENT POLYMER PARTICLES BY POLYMERIZING DROPLETS OF A MONOMER SOLUTION BASF SE (DE) 2018-11-21 EP claimed
EP-2922882-B1 A PROCESS FOR PRODUCING SURFACE-POSTCROSSLINKED WATER-ABSORBENT POLYMER PARTICLES BASF SE (DE) 2018-03-28 EP claimed
US-20180030218-A1 METHOD FOR PRODUCING WATER-ABSORBING POLYMER PARTICLES BY SUSPENSION POLYMERIZATION BASF SE (DE) 2018-02-01 US claimed
EP-3262106-A1 A PROCESS FOR PRODUCING SURFACE-POSTCROSSLINKED WATER-ABSORBENT POLYMER PARTICLES BY POLYMERIZING DROPLETS OF A MONOMER SOLUTION BASF SE (DE) 2018-01-03 EP claimed
CN-103254107-A Ezetimibe analogue and preparation method thereof UNIV DONGHUA 2013-08-21 CN claimed
US-20090271879-A1 ANALOGUES OF (-)-PICROPODOPHYLLIN, SYNTHESIS AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2009-10-29 US claimed
WO-2009100349-A1 ANALOGUES OF (-)-PICROPODOPHYLLIN, SYNTHESIS AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2009-08-13 WO claimed
US-7002020-B1 Oxazolidinone combinatorial libraries, compositions and methods of preparation PHARMACIA & UPJOHN COMPANY (US) 2006-02-21 US claimed
US-20020183371-A1 Oxazolidinone combinatorial libraries, compositions and methods of preparation GORDEEV MIKHAIL F (US) 2002-12-05 US claimed
JP-2002501059-A 2002-01-15 JP claimed
EP-1049682-A1 OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION Versicor, Inc. (US) 2000-11-08 EP claimed
US-6051721-A Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2000-04-18 US claimed
WO-1999037630-A1 OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION VERSICOR, INC. (US) 1999-07-29 WO claimed
WO-1999018109-A1 RING E-MODIFIED ANALOGUES OF (-)-PODOPHYLLOTOXIN AND ETOPOSIDE AND A METHOD FOR THEIR SYNTHESIS THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 1999-04-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183371-A1 Oxazolidinone combinatorial libraries, compositions and methods of preparation PAICS, CDK4, OXA1L NAAA 3387/4885KDM4E 1239/4885PIK3CD 57/4885
US-20090271879-A1 ANALOGUES OF (-)-PICROPODOPHYLLIN, SYNTHESIS AND USES THEREOF PPOX, HCCS, DHPS NAAA 4290/4885KDM4E 3896/4885PIK3CD 2887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.