SCHEMBL8516486

SCHEMBL8516486

Cc1c(C(C)(C)c2ccccc2)ccc(O)c1-c1c(O)ccc(S(=O)(=O)O)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
CYP3A4 P08684 1/20 0.37
CNR1 P21554 4/20 0.36
CNR2 P34972 4/20 0.36
TNNI3 P19429 1/20 0.35
TNNT2 P45379 1/20 0.35
TNNC1 P63316 1/20 0.35
HKDC1 Q2TB90 1/20 0.35
NR3C2 P08235 3/20 0.34
COMT P21964 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
MYC P01106 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
MPL P40238 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8516847 0.89 ESR1 (0.35) ALDH1A1ESR1ESR2CYP3A4CNR1
SCHEMBL8516783 0.89 NQO1 (0.35) ALDH1A1ESR1ESR2CYP3A4CNR1
SCHEMBL8370449 0.81 ESR1 (0.40) ALDH1A1ESR1ESR2CYP3A4CNR1
SCHEMBL8517228 0.80 NQO1 (0.41) ALDH1A1TNNI3TNNT2TNNC1HKDC1
SCHEMBL8370433 0.80 ESR1 (0.41) ALDH1A1ESR1ESR2CYP3A4CNR1
SCHEMBL27866164 0.75 ESR1 (0.48) ALDH1A1ESR1ESR2CYP3A4CNR1
SCHEMBL8541112 0.75 PGAM1 (0.36) ALDH1A1ESR1ESR2CYP3A4CNR1
SCHEMBL8365820 0.74 CNR1 (0.43) ALDH1A1ESR1ESR2CYP3A4CNR1
SCHEMBL8365842 0.74 CNR1 (0.40) ALDH1A1ESR1ESR2CYP3A4CNR1
SCHEMBL8365871 0.74 ESR1 (0.41) ALDH1A1ESR1ESR2CYP3A4CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed