SCHEMBL8516783

SCHEMBL8516783

Cc1ccc(S(=O)(=O)O)c(O)c1-c1c(O)ccc(C(C)(C)c2ccccc2)c1C

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.35
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
CNR1 P21554 3/20 0.33
CNR2 P34972 3/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
TNNI3 P19429 1/20 0.32
TNNT2 P45379 1/20 0.32
TNNC1 P63316 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
NR3C2 P08235 2/20 0.31
LDHA P00338 1/20 0.31
GLO1 Q04760 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8516847 0.90 ESR1 (0.35) NQO1ESR1ESR2CNR1CNR2
SCHEMBL8516486 0.89 ALDH1A1 (0.37) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL8516633 0.80 NQO1 (0.44) NQO1ESR2ALDH1A1MAPTKMT2A
SCHEMBL8370449 0.76 ESR1 (0.40) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL8517009 0.75 NQO1 (0.41) NQO1ESR2ALDH1A1CYP3A4MAPT
SCHEMBL8365857 0.74 ESR1 (0.41) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL8368892 0.74 ESR1 (0.41) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL8516702 0.74 ELANE (0.44) NQO1ESR1ESR2ALDH1A1CYP3A4
SCHEMBL8516648 0.74 TYR (0.38) NQO1ALDH1A1TNNI3TNNT2TNNC1
SCHEMBL8369543 0.73 ESR1 (0.40) ESR1ESR2CNR1CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed