SCHEMBL8516596

SCHEMBL8516596

CC(CC(c1ccccc1)c1cc(-c2ccc(O)cc2)cc(S(=O)(=O)O)c1O)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.36
GRIA4 P48058 1/20 0.34
ESR2 Q92731 3/20 0.34
ESR1 P03372 2/20 0.34
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
TSHR P16473 2/20 0.33
CYP1A2 P05177 1/20 0.33
ADAMTS4 O75173 1/20 0.33
PGAM1 P18669 1/20 0.33
UQCRB P14927 1/20 0.33
APP P05067 1/20 0.33
TYR P14679 1/20 0.33
MMP3 P08254 1/20 0.32
BCL2L1 Q07817 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8367569 0.94 TRPA1 (0.38) TRPA1GRIA4CYP3A4CYP2C9CYP2C19
SCHEMBL8370514 0.87 TRPA1 (0.40) TRPA1ESR1CYP3A4CYP2C9CYP2C19
SCHEMBL8516704 0.84 TYR (0.46) ESR2ESR1CYP3A4CYP2C9CYP2C19
SCHEMBL8368667 0.83 FABP3 (0.41) TRPA1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL8515906 0.82 TRPA1 (0.33) TRPA1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL8517116 0.82 TYR (0.43) ESR2ESR1CYP3A4CYP2C9CYP2C19
SCHEMBL8365850 0.82 TRPA1 (0.38) TRPA1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL8517301 0.81 TRPA1 (0.39) TRPA1GRIA4ESR2ESR1CYP3A4
SCHEMBL8516728 0.81 LMNA (0.40) TRPA1GRIA4ESR1CYP3A4CYP2C9
SCHEMBL8369544 0.81 CYP1A2 (0.51) TRPA1GRIA4ESR2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed