SCHEMBL8516600

SCHEMBL8516600

CCCc1cc(-c2cc(CCC)c(O)c(S(=O)(=O)O)c2)cc(C(C)(C)c2ccccc2)c1O

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 3/20 0.34
ESR2 Q92731 2/20 0.32
ALDH1A1 P00352 1/20 0.32
ESR1 P03372 1/20 0.32
CYP3A4 P08684 1/20 0.32
PTPN5 P54829 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PGAM1 P18669 1/20 0.32
GABRA1 P14867 3/20 0.31
GABRB2 P47870 3/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8370475 0.82 PTPN1 (0.40) NR3C2ESR2ALDH1A1ESR1CYP3A4
SCHEMBL8516720 0.82 HSD17B10 (0.39) ESR2ALDH1A1ESR1LMNAHPGD
SCHEMBL8516738 0.79 ESR2 (0.46) NR3C2ESR2ALDH1A1ESR1CYP3A4
SCHEMBL8369689 0.77 NR3C2 (0.38) NR3C2ESR2ALDH1A1ESR1CYP3A4
SCHEMBL8367639 0.77 NR3C2 (0.43) NR3C2ESR2ALDH1A1ESR1CYP3A4
SCHEMBL8516371 0.76 ALOX5 (0.48) ESR2ESR1LMNAHPGDHIF1A
SCHEMBL8517003 0.75 TYR (0.35) CYP3A4LMNAHPGDHIF1AHSD17B10
SCHEMBL8367622 0.74 TRPV1 (0.41) CYP3A4CNR1CNR2
SCHEMBL8369567 0.74 TRPV1 (0.41) CYP3A4CNR1CNR2
SCHEMBL8367502 0.74 ESR1 (0.44) NR3C2ESR2ALDH1A1ESR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed