SCHEMBL8516738

SCHEMBL8516738

CC(C)(c1ccccc1)c1cc(-c2ccc(O)cc2)cc(S(=O)(=O)O)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 8/20 0.46
ESR1 P03372 6/20 0.46
CYP3A4 P08684 2/20 0.46
ALDH1A1 P00352 1/20 0.46
PTPN1 P18031 1/20 0.38
MMP3 P08254 1/20 0.37
BCL2L1 Q07817 1/20 0.37
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
AR P10275 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
HTR6 P50406 1/20 0.36
ESRRG P62508 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8370475 0.93 PTPN1 (0.40) ESR2ESR1CYP3A4ALDH1A1PTPN1
SCHEMBL8369553 0.84 ESR2 (0.44) ESR2ESR1CYP3A4ALDH1A1AR
SCHEMBL8367502 0.81 ESR1 (0.44) ESR2ESR1CYP3A4ALDH1A1AR
SCHEMBL8367500 0.80 CYP3A4 (0.40) ESR2ESR1CYP3A4ALDH1A1TSHR
SCHEMBL8516600 0.79 NR3C2 (0.34) ESR2ESR1CYP3A4ALDH1A1HPGD
SCHEMBL8517188 0.78 ESR2 (0.50) ESR2ESR1CYP3A4ALDH1A1PTPN1
SCHEMBL8516572 0.78 HSD17B2 (0.40) ESR2ESR1CYP3A4ALDH1A1PTPN1
SCHEMBL8369784 0.77 ESR1 (0.40) ESR2ESR1CYP3A4ALDH1A1PTPN1
SCHEMBL8516622 0.77 ESR1 (0.52) ESR2ESR1MMP3BCL2L1HPGD
SCHEMBL8368763 0.77 PGAM1 (0.38) ESR2ESR1CYP3A4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed