Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516689 | 0.87 | ALDH1A1 (0.53) | ALDH1A1NPSR1CNR2CNR1PTPN1 | |
| Hydrochloric Acid SCHEMBL9116966 | 0.86 | ALDH1A1 (0.53) | ALDH1A1NPSR1CNR2CNR1PTPN1 | |
| SCHEMBL8516580 | 0.79 | CNR2 (0.49) | ALDH1A1NPSR1CNR2PTPN1NAAA | |
| SCHEMBL7193544 | 0.78 | ALDH1A1 (0.52) | ALDH1A1NPSR1CNR2CNR1MEN1 | |
| Hydrochloric Acid SCHEMBL9239580 | 0.78 | CNR2 (0.48) | ALDH1A1NPSR1CNR2PTPN1NAAA | |
| SCHEMBL9119461 | 0.75 | PTPN1 (0.46) | ALDH1A1NPSR1CNR2CNR1PTPN1 | |
| SCHEMBL31329235 | 0.75 | ALDH1A1 (0.79) | ALDH1A1NPSR1CNR2CNR1MEN1 | |
| SCHEMBL8369255 | 0.74 | ALDH1A1 (0.47) | ALDH1A1NPSR1CNR2 | |
| Hydrochloric Acid SCHEMBL9118183 | 0.74 | ALDH1A1 (0.47) | ALDH1A1NPSR1CNR2 | |
| SCHEMBL8366085 | 0.73 | PTPN11 (0.56) | ALDH1A1NPSR1PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738144-A4 | PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF | SMITHKLINE BEECHAM CORP (US) | 1999-06-30 | — | — | EP | claimed |
| EP-0738144-A1 | PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 1996-10-23 | — | — | EP | claimed |