Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 6/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSH | P09668 | 2/20 | 0.51 |
| ▸ | CTSC | P53634 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354660 | 1.00 | CTSB (0.51) | CTSBCTSKCTSSCTSHCTSC | |
| SCHEMBL7349455 | 0.95 | CTSB (0.56) | CTSBCTSKCTSSCTSHCTSC | |
| SCHEMBL7355598 | 0.95 | CTSB (0.56) | CTSBCTSKCTSSCTSHCTSC | |
| SCHEMBL7352317 | 0.89 | CTSB (0.48) | CTSBCTSKCTSSCTSHCTSC | |
| SCHEMBL7360670 | 0.86 | CTSB (0.47) | CTSBCTSKCTSSCTSHCTSC | |
| SCHEMBL7354313 | 0.86 | CTSB (0.51) | CTSBCTSKCTSSCTSHCTSC | |
| SCHEMBL7352274 | 0.86 | CTSB (0.47) | CTSBCTSKCTSSCTSHCTSC | |
| SCHEMBL7350474 | 0.86 | CTSL (0.44) | CTSBCTSKCTSSCTSHCTSC | |
| Bromide SCHEMBL7353802 | 0.85 | CTSB (0.44) | CTSBCTSKCTSSCTSHCTSC | |
| SCHEMBL7360548 | 0.85 | CTSB (0.46) | CTSBCTSKCTSSCTSHCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756625-A4 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | ARRIS PHARM CORP (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0756625-A1 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-02-05 | — | — | EP | disclosed |