Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8516660

CCn1cc(-c2nc3ccc(C(=O)OC)cc3n(CCCCCN)c2=O)c2ccccc21.O=C(O)C(F)(F)F

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 2/20 0.46
ACSS2 Q9NR19 1/20 0.44
CA12 O43570 4/20 0.42
CA1 P00915 4/20 0.42
CA2 P00918 4/20 0.42
CA9 Q16790 4/20 0.42
TLR8 Q9NR97 2/20 0.40
TLR7 Q9NYK1 1/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPK1 P28482 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
USP2 O75604 1/20 0.38
CYP3A4 P08684 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
CNR2 P34972 1/20 0.38
NR4A2 P43354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL8516150 0.97 CFTR (0.47) CFTRACSS2CA12CA1CA2
Trifluoroacetic Acid SCHEMBL8516818 0.92 CFTR (0.42) CFTRACSS2CA12CA1CA2
Trifluoroacetic Acid SCHEMBL8516149 0.90 CFTR (0.45) CFTRACSS2CA12CA1CA2
Trifluoroacetic Acid SCHEMBL8516484 0.90 CFTR (0.45) CFTRACSS2CA12CA1CA2
Trifluoroacetic Acid SCHEMBL8367871 0.89 CFTR (0.46) CFTRACSS2CA12CA1CA2
Trifluoroacetic Acid SCHEMBL8368543 0.89 CFTR (0.42) CFTRACSS2CA12CA1CA2
SCHEMBL8365741 0.88 CA12 (0.43) CFTRACSS2CA12CA1CA2
Trifluoroacetic Acid SCHEMBL8516338 0.88 ALDH1A1 (0.45) CA12CA1CA2CA9KDM4E
Trifluoroacetic Acid SCHEMBL8516292 0.88 ALDH1A1 (0.44) CFTRMAPK1NPSR1ALDH1A1CYP1A2
Trifluoroacetic Acid SCHEMBL8515708 0.87 CFTR (0.46) CFTRACSS2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999046260-A1 NEW COMPOUNDS ASTRAZENECA AB (SE) 1999-09-16 WO claimed