Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14804610 | 1.00 | OPRM1 (0.38) | OPRM1CYP4F2CYP4A11SLC6A2SLC6A4 | |
| SCHEMBL16310454 | 0.89 | OPRM1 (0.42) | OPRM1CYP4F2CYP4A11SMYD3NPSR1 | |
| Hydrochloric Acid SCHEMBL31719805 | 0.88 | CYP4F2 (0.41) | OPRM1CYP4F2CYP4A11SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL23727034 | 0.87 | OPRM1 (0.41) | OPRM1CYP4F2CYP4A11SMYD3NPSR1 | |
| SCHEMBL15367602 | 0.86 | CYP2D6 (0.42) | OPRM1CYP4F2CYP4A11SLC6A2SLC6A4 | |
| SCHEMBL19797415 | 0.84 | CYP4F2 (0.38) | OPRM1CYP4F2CYP4A11NPSR1 | |
| SCHEMBL13118615 | 0.84 | OPRM1 (0.45) | OPRM1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL13854455 | 0.84 | CYP4F2 (0.37) | OPRM1CYP4F2CYP4A11SLC6A2SLC6A4 | |
| SCHEMBL2470817 | 0.84 | CYP4F2 (0.37) | OPRM1CYP4F2CYP4A11SLC6A2SLC6A4 | |
| SCHEMBL2470075 | 0.81 | OPRM1 (0.35) | OPRM1CYP4F2CYP4A11SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392803-B1 | Novel compounds | BEECHAM GROUP PLC (GB) | 2004-06-16 | — | — | EP | disclosed |