SCHEMBL2470817

SCHEMBL2470817

COCC1(C(=O)OC)CCNC1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
OPRM1 P35372 1/20 0.34
SLC6A2 P23975 14/20 0.34
SLC6A4 P31645 14/20 0.34
SLC6A3 Q01959 14/20 0.34
CYP2D6 P10635 12/20 0.34
NPSR1 Q6W5P4 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
KDM4E B2RXH2 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13854455 1.00 CYP4F2 (0.37) CYP4F2CYP4A11OPRM1SLC6A2SLC6A4
Cadaverine Tartrate SCHEMBL4218350 0.89 OPRM1 (0.32) CYP4F2CYP4A11OPRM1SLC6A2SLC6A4
SCHEMBL29896716 0.84 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3CYP2D6CYP1A2
SCHEMBL14804610 0.84 OPRM1 (0.38) CYP4F2CYP4A11OPRM1SLC6A2SLC6A4
SCHEMBL8516845 0.84 OPRM1 (0.38) CYP4F2CYP4A11OPRM1SLC6A2SLC6A4
SCHEMBL15367602 0.81 CYP2D6 (0.42) CYP4F2CYP4A11OPRM1SLC6A2SLC6A4
SCHEMBL28383552 0.80 CYP2D6 (0.34) CYP4F2CYP4A11SLC6A2SLC6A4SLC6A3
SCHEMBL2470075 0.79 OPRM1 (0.35) CYP4F2CYP4A11OPRM1SLC6A2SLC6A4
SCHEMBL17031937 0.78 CYP4F2 (0.48) CYP4F2CYP4A11CYP2D6NPSR1
SCHEMBL13092542 0.78 CYP4F2 (0.34) CYP4F2CYP4A11OPRM1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2017-10-05 US claimed
US-20160272733-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECHNOLOGY LTD. (CN) 2016-09-22 US claimed
EP-4712961-A2 KRAS G12S AND G12C INHIBITORS Mirati Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024238633-A2 KRAS G12S AND G12C INHIBITORS Mirati Therapeutics, Inc. (US) 2024-11-21 WO disclosed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 US disclosed
US-10208146-B2 Catalyst component for olefin polymerization and application thereof BEIJING LIHE TECHNOLOGY LTD. (CN) 2019-02-19 US disclosed
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2017-12-14 US disclosed
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2017-10-05 US disclosed
US-20160272733-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF BEIJING LIHE TECHNOLOGY LTD. (CN) 2016-09-22 US disclosed
US-8546404-B2 Compounds that are ERK inhibitors MERCK SHARP & DOHME (US) 2013-10-01 US disclosed
US-8546404-B2 Compounds that are ERK inhibitors MERCK SHARP & DOHME (US) 2013-10-01 US disclosed
US-20070232610-A1 Novel compounds that are ERK inhibitors SCHERING CORPORATION 2007-10-04 US disclosed
US-20070232610-A1 Novel compounds that are ERK inhibitors SCHERING CORPORATION 2007-10-04 US disclosed
US-20070232610-A1 Novel compounds that are ERK inhibitors SCHERING CORPORATION 2007-10-04 US disclosed
WO-2007097937-A1 PYRROLIDINE DERIVATIVES AS ERK INHIBITORS SCHERING CORPORATION (US) 2007-08-30 WO disclosed
WO-2007097937-A1 PYRROLIDINE DERIVATIVES AS ERK INHIBITORS SCHERING CORPORATION (US) 2007-08-30 WO disclosed
US-20070191604-A1 Novel compounds that are ERK inhibitors SCHERING CORPORATION 2007-08-16 US disclosed
US-20070191604-A1 Novel compounds that are ERK inhibitors SCHERING CORPORATION 2007-08-16 US disclosed
US-20070191604-A1 Novel compounds that are ERK inhibitors SCHERING CORPORATION 2007-08-16 US disclosed
WO-2007070398-A1 POLYCYCLIC INDAZOLE DERIVATIVES THAT ARE ERK INHIBITORS SCHERING CORPORATION (US) 2007-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191604-A1 Novel compounds that are ERK inhibitors MAPK1, MAPK4, MAPKAPK2 CYP4F2 2249/4885CYP4A11 2627/4885OPRM1 2391/4885
US-10208146-B2 Catalyst component for olefin polymerization and application thereof TEC, ETFA, TECR CYP4F2 31/4885CYP4A11 171/4885OPRM1 303/4885
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B CYP4F2 148/4885CYP4A11 660/4885OPRM1 13/4885
US-20070232610-A1 Novel compounds that are ERK inhibitors MAPK1, MAPK4, MAPKAPK2 CYP4F2 2249/4885CYP4A11 2627/4885OPRM1 2391/4885
US-20170283530-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF TEC, ETFA, TECR CYP4F2 31/4885CYP4A11 171/4885OPRM1 303/4885
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, COG7, COG4 CYP4F2 251/4885CYP4A11 1061/4885OPRM1 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.