Acetone

Acetone

SCHEMBL8516889

CC(=O)C(CO)CO.CC(C)=O.CC(C)=O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
SLC1A1 P43005 1/20 0.35
TSHR P16473 2/20 0.33
KISS1R Q969F8 3/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 3/20 0.32
OR51E2 Q9H255 1/20 0.32
HDAC7 Q8WUI4 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
TGFBR1 P36897 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL8844214 1.00 LMNA (0.40) LMNASLC1A1TSHRKISS1RUSP2
SCHEMBL3042219 0.97
SCHEMBL7805782 0.81
SCHEMBL3095460 0.81
SCHEMBL8679924 0.79 ALDH1A1 (0.46) SLC1A1ALDH1A1TDP1TRPA1
SCHEMBL22567183 0.79
SCHEMBL27338696 0.79
SCHEMBL3958833 0.79
SCHEMBL14725173 0.79 ALDH1A1 (0.46) SLC1A1ALDH1A1TDP1TRPA1
SCHEMBL9270192 0.77 MME (0.44) LMNASLC1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1098850-C 3 alpha-alkylacyloxy-6 beta-alkylacyoxy tropane compounds and their prepn. SHANGHAI NO 2 MEDICAL UNIV (CN) 2003-01-15 CN disclosed
CN-1323798-A 3 alpha-alkylacyloxy-6 beta-alkylacyoxy tropane compounds and their prepn. SHANGHAI NO 2 MEDICAL UNIV (CN) 2001-11-28 CN disclosed
US-5998496-A ABSORBING RADIATION SPECTRA GROUP LIMITED, INC. (US) 1999-12-07 US disclosed
EP-0871607-A4 PHOTOSENSITIVE INTRAMOLECULAR ELECTRON TRANSFER COMPOUNDS SPECTRA GROUP LTD INC (US) 1999-09-29 EP disclosed
EP-0871607-A1 PHOTOSENSITIVE INTRAMOLECULAR ELECTRON TRANSFER COMPOUNDS SPECTRA GROUP LIMITED INC (US) 1998-10-21 EP disclosed
WO-1997016406-A1 PHOTOSENSITIVE INTRAMOLECULAR ELECTRON TRANSFER COMPOUNDS SPECTRA GROUP LIMITED, INC. (US) 1997-05-09 WO disclosed