Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516904 | 1.00 | ALDH1A1 (0.46) | ALDH1A1NOS3NOS1MAPTRAB9A | |
| SCHEMBL28557957 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTRAB9AKDM4EMEN1 | |
| Bicarbonate SCHEMBL10710256 | 0.75 | ALDH1A1 (0.41) | ALDH1A1NOS3NOS1MAPTRAB9A | |
| SCHEMBL6536579 | 0.74 | SIRT2 (0.38) | ALDH1A1NOS3NOS1MAPTRAB9A | |
| SCHEMBL637260 | 0.74 | KDM4E (0.38) | ALDH1A1NOS3NOS1MAPTRAB9A | |
| SCHEMBL637259 | 0.74 | KDM4E (0.38) | ALDH1A1NOS3NOS1MAPTRAB9A | |
| SCHEMBL30566741 | 0.74 | APAF1 (0.39) | MAPTRAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL28549171 | 0.72 | TDP1 (0.41) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL30354558 | 0.71 | KDM4E (0.46) | ALDH1A1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL11292213 | 0.71 | ALDH1A1 (0.37) | ALDH1A1MAPTRAB9AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999056567-A1 | ANTI-MICROBIAL AGENTS | ABBOTT DEANE NZ LIMITED (NZ) | 1999-11-11 | — | — | WO | disclosed |