Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8516605 | 0.91 | KMT2A (0.49) | MEN1KMT2ACYP1A2USP2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8517292 | 0.89 | KMT2A (0.43) | MEN1KMT2ACYP1A2USP2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8516759 | 0.88 | ALDH1A1 (0.46) | MEN1KMT2ACYP1A2USP2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8516604 | 0.86 | CA12 (0.41) | MEN1KMT2ACYP1A2USP2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8517401 | 0.86 | USP2 (0.41) | MEN1KMT2ACYP1A2USP2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8515754 | 0.84 | CYP1A2 (0.40) | MEN1KMT2ACYP1A2USP2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8516685 | 0.81 | MEN1 (0.40) | MEN1KMT2ACYP1A2USP2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8517010 | 0.81 | KMT2A (0.47) | MEN1KMT2ACYP1A2USP2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8515904 | 0.80 | ALDH1A1 (0.45) | MEN1KMT2ACYP1A2USP2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL8516361 | 0.80 | KMT2A (0.46) | MEN1KMT2ACYP1A2USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |