Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 9/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.38 |
| ▸ | CASP1 | P29466 | 7/20 | 0.38 |
| ▸ | CASP7 | P55210 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | HBB | P68871 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8516685 | 0.91 | MEN1 (0.40) | USP2CYP1A2CYP3A4CASP1CASP7 | |
| Trifluoroacetic Acid SCHEMBL8516825 | 0.89 | CA12 (0.40) | CA12CA1CA9CA2USP2 | |
| Trifluoroacetic Acid SCHEMBL8516989 | 0.86 | MEN1 (0.46) | USP2CYP1A2CYP3A4CASP1CASP7 | |
| Trifluoroacetic Acid SCHEMBL8515856 | 0.86 | CA12 (0.38) | CA12CA1CA9CA2USP2 | |
| Trifluoroacetic Acid SCHEMBL8367871 | 0.85 | CFTR (0.46) | CA12CA1CA9CA2USP2 | |
| Trifluoroacetic Acid SCHEMBL8516078 | 0.81 | USP2 (0.39) | USP2CYP1A2CYP3A4CASP1CASP7 | |
| SCHEMBL8516687 | 0.80 | USP2 (0.33) | USP2CYP1A2CYP3A4CASP1CASP7 | |
| Trifluoroacetic Acid SCHEMBL8365238 | 0.80 | MAPT (0.44) | USP2MEN1KMT2APDE4BPDE4D | |
| Trifluoroacetic Acid SCHEMBL8366714 | 0.80 | LMNA (0.43) | USP2CYP1A2CYP3A4CASP1CASP7 | |
| Trifluoroacetic Acid SCHEMBL8516666 | 0.79 | USP2 (0.38) | USP2CYP1A2CYP3A4CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |