SCHEMBL8517059

SCHEMBL8517059

O=S(=O)(O)c1cc(-c2cccc(S(=O)(=O)O)c2O)ccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGAM1 P18669 1/20 0.44
HPGD P15428 4/20 0.41
HSD17B10 Q99714 4/20 0.41
LMNA P02545 2/20 0.41
HIF1A Q16665 1/20 0.41
MAPT P10636 5/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
HPGDS O60760 1/20 0.40
APP P05067 1/20 0.40
MCL1 Q07820 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
ALPL P05186 2/20 0.39
ALPI P09923 1/20 0.39
ALPG P10696 1/20 0.39
DNMT1 P26358 1/20 0.39
STAT3 P40763 1/20 0.39
MMP14 P50281 2/20 0.39
KDM4A O75164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9169234 0.86 APP (0.47) PGAM1HPGDHSD17B10LMNAHIF1A
SCHEMBL8516890 0.83 ESR2 (0.47) PGAM1HPGDHSD17B10LMNAHIF1A
SCHEMBL8517162 0.81 PGAM1 (0.44) PGAM1LMNAMEN1KMT2ASTAT3
SCHEMBL1535883 0.80 HSD17B10 (0.52) HPGDHSD17B10LMNAHIF1AMAPT
SCHEMBL8517108 0.80 PGAM1 (0.47) PGAM1HPGDHSD17B10LMNAMAPT
SCHEMBL8368643 0.79 HDAC4 (0.52) PGAM1HPGDHSD17B10HIF1ASTAT3
SCHEMBL8517286 0.79 HSD17B10 (0.40) PGAM1HPGDHSD17B10LMNAHIF1A
SCHEMBL8517718 0.78 PGAM1 (0.41) PGAM1APPMCL1L3MBTL1ALPL
SCHEMBL28993725 0.78 HSD17B10 (0.50) HPGDHSD17B10LMNAHIF1AMAPT
Potassium SCHEMBL30364442 0.78 HSD17B10 (0.50) HPGDHSD17B10LMNAHIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed