Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HNF4A | P41235 | 1/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517162 | 0.87 | PGAM1 (0.44) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL9246392 | 0.86 | HDAC4 (0.53) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL8517108 | 0.86 | PGAM1 (0.47) | PGAM1HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL28019701 | 0.85 | PGAM1 (0.49) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL8909039 | 0.85 | HNF4A (0.43) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL2521857 | 0.85 | PTGS2 (0.44) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL17888508 | 0.84 | NPC1 (0.44) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL29743050 | 0.84 | CASP1 (0.47) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL232659 | 0.84 | CASP1 (0.47) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL29700169 | 0.83 | PTGS2 (0.52) | HDAC4HDAC2HDAC8HDAC6HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1444477-A | Thrombopoietin mimetics | SMITHKLINE BEECHAM CORP (US) | 2003-09-24 | — | — | CN | claimed |
| CN-1444477-A | Thrombopoietin mimetics | SMITHKLINE BEECHAM CORP (US) | 2003-09-24 | — | — | CN | disclosed |
| EP-0714785-B1 | Sulfonated phenol (salt) containing color-developing agents and color-developing sheets | MITSUI CHEMICALS INC (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5647896-A | MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0714785-A1 | Sulfonated phenol (salt) containing color-developing agents and color-developing sheets | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-06-05 | — | — | EP | disclosed |