Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596123 | 0.82 | ADRA1D (0.64) | MEN1KMT2AMAPTDRD2DRD4 | |
| SCHEMBL8517234 | 0.76 | MEN1 (0.55) | MEN1KMT2AMAPTDRD2DRD4 | |
| SCHEMBL8370485 | 0.76 | MEN1 (0.65) | MEN1KMT2AMAPTDRD2DRD4 | |
| SCHEMBL7602249 | 0.75 | ADRA1D (0.77) | MEN1KMT2AMAPTDRD2DRD4 | |
| SCHEMBL7597676 | 0.74 | ADRA1D (0.63) | MEN1KMT2AMAPTDRD2DRD4 | |
| SCHEMBL7603299 | 0.73 | ADRA1D (0.62) | MEN1KMT2AMAPTDRD2DRD4 | |
| SCHEMBL7596968 | 0.73 | ADRA1D (0.59) | MEN1KMT2AMAPTDRD2DRD4 | |
| SCHEMBL7597602 | 0.70 | ADRA1D (0.58) | MEN1KMT2AMAPTDRD2DRD4 | |
| SCHEMBL8371534 | 0.70 | ALDH1A1 (0.60) | MEN1KMT2AMAPTDRD2DRD4 | |
| SCHEMBL7596145 | 0.69 | ADRA1D (0.56) | MEN1KMT2AMAPTDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891344-A1 | ALPHA 1-ADRENERGIC RECEPTOR ANTAGONISTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997037983-A1 | α1-ADRENERGIC RECEPTOR ANTAGONISTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1997-10-16 | — | — | WO | disclosed |