Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517300 | 1.00 | GRM2 (0.41) | GRM2HTR2ARPA1GPR84ICMT | |
| SCHEMBL8517303 | 1.00 | GRM2 (0.41) | GRM2HTR2ARPA1GPR84ICMT | |
| SCHEMBL8517305 | 1.00 | GRM2 (0.41) | GRM2HTR2ARPA1GPR84ICMT | |
| SCHEMBL8518373 | 0.91 | GPR84 (0.34) | GRM2HTR2AGPR84MAOB | |
| SCHEMBL8518375 | 0.91 | GPR84 (0.34) | GRM2HTR2AGPR84MAOB | |
| SCHEMBL8518370 | 0.91 | GPR84 (0.34) | GRM2HTR2AGPR84MAOB | |
| SCHEMBL8518372 | 0.91 | GPR84 (0.34) | GRM2HTR2AGPR84MAOB | |
| SCHEMBL8517341 | 0.89 | SLC6A3 (0.40) | GPR84MAOB | |
| SCHEMBL8517555 | 0.89 | CYP17A1 (0.38) | GPR84PGRNR1H4MAOB | |
| SCHEMBL8517336 | 0.89 | SLC6A3 (0.40) | GPR84MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |