Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311774 | 0.90 | ACACB (0.32) | PDGFRBPDGFRAKCNH2 | |
| SCHEMBL8517281 | 0.90 | GRM2 (0.35) | PDGFRBPDGFRAKCNH2CNR1CNR2 | |
| SCHEMBL8517255 | 0.87 | LMNA (0.36) | PDGFRBPDGFRANPC1RAB9ACNR1 | |
| SCHEMBL9312325 | 0.86 | PDGFRB (0.32) | PDGFRBPDGFRAKCNH2SLC6A3HRH1 | |
| SCHEMBL9312309 | 0.86 | PDGFRB (0.32) | PDGFRBPDGFRAKCNH2SLC6A3HRH1 | |
| SCHEMBL9312335 | 0.86 | PDGFRB (0.32) | PDGFRBPDGFRAKCNH2SLC6A3HRH1 | |
| SCHEMBL9312319 | 0.86 | PDGFRB (0.32) | PDGFRBPDGFRAKCNH2SLC6A3HRH1 | |
| SCHEMBL8381991 | 0.85 | S1PR3 (0.36) | PDGFRBPDGFRAKCNH2SLC6A3HRH1 | |
| SCHEMBL8517670 | 0.84 | NPY5R (0.34) | PDGFRBPDGFRA | |
| SCHEMBL9312631 | 0.82 | PDGFRB (0.31) | PDGFRBPDGFRAKCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |