SCHEMBL8517459

SCHEMBL8517459

CC(c1ccccc1)c1cc(-c2ccc(O)cc2)c(O)c(S(=O)(=O)O)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGAM1 P18669 1/20 0.40
TYR P14679 1/20 0.39
ESR1 P03372 6/20 0.39
ESR2 Q92731 5/20 0.39
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
APP P05067 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
BACE1 P56817 1/20 0.35
TSHR P16473 1/20 0.34
ABL1 P00519 2/20 0.34
ABCB1 P08183 2/20 0.34
BCR P11274 2/20 0.34
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8516752 0.99 ESR1 (0.41) PGAM1TYRESR1ESR2PDCD1
SCHEMBL8370446 0.93 PGAM1 (0.42) PGAM1TYRCYP2C9CYP2C19BACE1
SCHEMBL8367512 0.92 PGAM1 (0.41) PGAM1TYRESR1ESR2PDCD1
SCHEMBL8516052 0.84 TYR (0.38) PGAM1TYRESR1MAPTKMT2A
SCHEMBL8517301 0.84 TRPA1 (0.39) PGAM1ESR1ESR2APPCYP3A4
SCHEMBL8369774 0.83 PGAM1 (0.44) PGAM1TYRESR1ESR2PDCD1
SCHEMBL8516626 0.83 PGAM1 (0.43) PGAM1TYRCYP3A4MAPTKMT2A
SCHEMBL8516873 0.82 PGAM1 (0.40) PGAM1TYRESR1ESR2PDCD1
SCHEMBL8367628 0.80 PGAM1 (0.42) PGAM1TYRCYP2C9MAPTKMT2A
SCHEMBL8517116 0.80 TYR (0.43) PGAM1TYRESR1ESR2PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed