Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311978 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2RAB9AHSD17B10NPC1LMNA | |
| SCHEMBL8517492 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2RAB9AHSD17B10NPC1LMNA | |
| SCHEMBL8517493 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2RAB9AHSD17B10NPC1LMNA | |
| SCHEMBL9311921 | 0.91 | LMNA (0.35) | SMN1; SMN2RAB9AHSD17B10NPC1LMNA | |
| SCHEMBL8517254 | 0.91 | LMNA (0.35) | SMN1; SMN2RAB9AHSD17B10NPC1LMNA | |
| SCHEMBL8517258 | 0.91 | LMNA (0.35) | SMN1; SMN2RAB9AHSD17B10NPC1LMNA | |
| SCHEMBL9312756 | 0.88 | CNR1 (0.31) | RARBCNR1 | |
| SCHEMBL8517918 | 0.88 | CNR1 (0.31) | RARBCNR1 | |
| SCHEMBL8517917 | 0.88 | CNR1 (0.31) | RARBCNR1 | |
| SCHEMBL8517916 | 0.88 | CNR1 (0.31) | RARBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |