SCHEMBL463385

SCHEMBL463385

C=CCOC(=O)C(C)(C)Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.42
MAPT P10636 4/20 0.40
TSHR P16473 2/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
RHOA P61586 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
PKM P14618 1/20 0.33
SNCA P37840 1/20 0.33
APP P05067 1/20 0.33
ADRB2 P07550 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18095075 0.83 ALDH1A1 (0.38) CYP3A4MAPTTSHRCACNA1BAPBA1
SCHEMBL194466 0.82 TSHR (0.42) CYP3A4MAPTTSHRCACNA1BAPBA1
SCHEMBL7095889 0.82 CYP3A4 (0.45) CYP3A4MAPTTSHRCACNA1BAPBA1
SCHEMBL7866089 0.82 TSHR (0.42) CYP3A4MAPTTSHRCACNA1BAPBA1
SCHEMBL3965671 0.82 TK1 (0.40) NPSR1GAA
SCHEMBL13644865 0.82 TK1 (0.40) NPSR1GAA
SCHEMBL16664312 0.81 ALDH1A1 (0.41) CYP3A4MAPTTSHRCACNA1BAPBA1
SCHEMBL6947345 0.81 ALDH1A1 (0.41) CYP3A4MAPTTSHRCACNA1BAPBA1
SCHEMBL6194635 0.80 TSHR (0.41) CYP3A4MAPTTSHRCACNA1BAPBA1
SCHEMBL4675516 0.80 TSHR (0.41) CYP3A4MAPTTSHRCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119699322-A Preparation process and application of thiamethoxam water dispersible granule 山东中新科农生物科学有限公司 2025-03-28 CN claimed
US-20240304812-A1 SILICON COMPOUND, PREPARATION METHOD THEREOF AND LITHIUM BATTERY NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2024-09-12 US claimed
CN-114262414-B Comb-type ultra-high molecular weight polymer and synthesis method thereof 长春市兆兴新材料技术有限责任公司 2024-07-05 CN claimed
CN-112500537-B Silicon compound, preparation method thereof and lithium battery 王復民 2024-06-04 CN claimed
CN-113501894-B Methacrylate copolymer based on photocatalysis and medical optical polymer 福州大学 2022-07-26 CN claimed
CN-113717301-B High-activity free radical polymerization system based on oxygen-heterocyclic aromatic photocatalyst 福州大学 2022-05-24 CN claimed
CN-113717301-A High-activity free radical polymerization system based on oxygen-heterocyclic photocatalyst 福州大学 2021-11-30 CN claimed
CN-112851480-A Biological extraction method of resveratrol 唐美荣 2021-05-28 CN claimed
US-20210079026-A1 SILICON COMPOUND, PREPARATION METHOD THEREOF AND LITHIUM BATTERY NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2021-03-18 US claimed
CN-112500537-A Silicon compound, preparation method thereof and lithium battery 王復民 2021-03-16 CN claimed
EP-1606323-A1 POLYMERISATION OF ETHYLENICALLY UNSATURATED MONOMERS Imperial Chemical Industries PLC (GB) 2005-12-21 EP claimed
US-20050113543-A1 Alpha, omega-allyl terminated linear poly(methacrylic acid) macromonomers for end-linked hydrogels and method of preparation MORNINGSIDE, COLUMBIA UNIVERSITY OF NY 2005-05-26 US claimed
US-6897333-B2 Process for the preparation of fibrates SOLCHEM ITALIANA S.P.A. (IL) 2005-05-24 US claimed
WO-2004085494-A1 POLYMERISATION OF ETHYLENICALLY UNSATURATED MONOMERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2004-10-07 WO claimed
US-20040073058-A1 Process for the preparation of fibrates OLON S.P.A. (IT) 2004-04-15 US claimed
WO-2003101934-A1 α,φ-ALLYL TERMINATED LINEAR POLY(METHACRYLIC ACID) MACROMONOMERS FOR END-LINKED HYDROGELS AND METHOD OF PREPARATION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2003-12-11 WO claimed
EP-1366013-A1 A PROCESS FOR THE PREPARATION OF FIBRATES Solchem Italiana S.p.A (IT) 2003-12-03 EP claimed
WO-2002062743-A1 A PROCESS FOR THE PREPARATION OF FIBRATES SOLCHEM ITALIANA S.P.A. (IT) 2002-08-15 WO claimed
EP-0245156-B1 PREPARATION OF FIBRATES FOURNIER INNOVATION ET SYNERGIE (FR) 1990-01-03 EP claimed
US-4739101-A Method for the preparation of fibrates FOURNIER INNOVATION ET SYNERGIE (FR) 1988-04-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040073058-A1 Process for the preparation of fibrates CPT1A, CES1, CPT1B CYP3A4 46/4885MAPT 4593/4885TSHR 1616/4885
US-20210079026-A1 SILICON COMPOUND, PREPARATION METHOD THEREOF AND LITHIUM BATTERY NCL, LMNB1, SLFN12 CYP3A4 1551/4885MAPT 3884/4885TSHR 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.