Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL18398854 | 0.80 | — | — | |
| Isobutyraldehyde SCHEMBL9350918 | 0.79 | — | — | |
| Isobutyraldehyde SCHEMBL427264 | 0.77 | LMNA (0.67) | LMNA | |
| Ether SCHEMBL7593160 | 0.76 | — | — | |
| Ether SCHEMBL7738174 | 0.75 | LMNA (0.44) | LMNAALDH1A1TSHR | |
| Isobutyraldehyde SCHEMBL2996 | 0.75 | — | — | |
| Isobutyraldehyde SCHEMBL18287436 | 0.75 | — | — | |
| Isobutyraldehyde SCHEMBL788159 | 0.75 | ADH1B (0.38) | TSHR | |
| Isobutyraldehyde SCHEMBL2635854 | 0.75 | ADH1B (0.38) | TSHR | |
| Ether SCHEMBL347669 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962507-A | BLOCKING CHOLESTEROL BIOSYNTHESIS | DR. KARL THOMAE GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| US-5726205-A | ANTICHOLESTEROL AGENTS | KARL THOMAE GMBH (DE) | 1998-03-10 | — | — | US | disclosed |
| CN-1057257-A | The new intermediate of new imdazole derivatives and method for making thereof, gained, as the application of medicine with contain their pharmaceutical composition | ROUSSEL UCLAF (FR) | 1991-12-25 | — | — | CN | disclosed |