Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | POLG | P54098 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5488005 | 0.88 | POLB (0.39) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL2365610 | 0.88 | POLG (0.38) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL16987259 | 0.87 | LMNA (0.45) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL3292628 | 0.87 | DNMT1 (0.50) | LMNAPDE3AMTORPOLBPDE4D | |
| SCHEMBL15301518 | 0.82 | TYMP (0.35) | POLB | |
| SCHEMBL16131335 | 0.82 | TYMP (0.35) | POLB | |
| SCHEMBL20710377 | 0.82 | KDM4E (0.38) | POLBADRB1DNMT1KDM4E | |
| SCHEMBL15216125 | 0.81 | KDM4E (0.36) | POLBKDM4E | |
| SCHEMBL5480814 | 0.80 | POLG (0.32) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL3278946 | 0.80 | KDM4E (0.48) | PDE3APOLBP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912340-A | FORMING STABLE HYBRID WITH DNA, RNA | EPOCH PHARMACEUTICALS, INC. (US) | 1999-06-15 | — | — | US | disclosed |