Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88581 | 0.70 | CASP3 (0.48) | POLBCYP3A4ALDH1A1CASP3L3MBTL1 | |
| SCHEMBL16116448 | 0.70 | — | — | |
| SCHEMBL288566 | 0.70 | CYP3A4 (0.46) | POLBCYP3A4ALDH1A1CASP3CYP1A2 | |
| SCHEMBL8903951 | 0.70 | CYP3A4 (0.46) | POLBCYP3A4ALDH1A1CASP3CYP1A2 | |
| SCHEMBL474426 | 0.67 | CYP3A4 (0.42) | POLBCYP3A4ALDH1A1CASP3CYP1A2 | |
| SCHEMBL723082 | 0.67 | POLB (0.43) | POLBCYP3A4ALDH1A1CASP3CYP1A2 | |
| SCHEMBL20204870 | 0.67 | POLB (0.37) | POLBCYP3A4ALDH1A1CASP3CYP1A2 | |
| SCHEMBL16197017 | 0.67 | NR1I2 (0.31) | — | |
| SCHEMBL7038598 | 0.66 | CASP3 (0.54) | POLBCYP3A4ALDH1A1CASP3L3MBTL1 | |
| SCHEMBL4553513 | 0.65 | CYP3A4 (0.41) | POLBCYP3A4ALDH1A1CASP3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661310-B1 | Cyclo-olefincopolymers and process for their preparation | TICONA GMBH (DE) | 1999-07-21 | — | — | EP | disclosed |
| EP-0661308-B1 | Cyclo-olefin copolymers and process for their preparation | TICONA GMBH (DE) | 1999-06-02 | — | — | EP | disclosed |
| US-5756623-A | MOLDING MATERIALS FOR COMPRESSION MOLDING | HOECHST AG (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0661310-A2 | Cyclo-olefincopolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0661308-A2 | Cyclo-olefin copolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |