Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 2/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88581 | 0.75 | CASP3 (0.48) | POLBALDH1A1CASP3CYP3A4L3MBTL1 | |
| SCHEMBL8517854 | 0.67 | POLB (0.40) | POLBALDH1A1CASP3CYP3A4L3MBTL1 | |
| SCHEMBL8412790 | 0.67 | — | — | |
| SCHEMBL21320662 | 0.65 | PTGS1 (0.46) | ALDH1A1CYP1A2MAPTLMNAMGLL | |
| SCHEMBL720380 | 0.64 | CYP3A4 (0.39) | POLBALDH1A1CASP3CYP3A4L3MBTL1 | |
| SCHEMBL7038598 | 0.62 | CASP3 (0.54) | POLBALDH1A1CASP3CYP3A4L3MBTL1 | |
| SCHEMBL16116448 | 0.62 | — | — | |
| SCHEMBL8903951 | 0.62 | CYP3A4 (0.46) | POLBALDH1A1CASP3CYP3A4L3MBTL1 | |
| SCHEMBL288566 | 0.62 | CYP3A4 (0.46) | POLBALDH1A1CASP3CYP3A4L3MBTL1 | |
| SCHEMBL729399 | 0.62 | ALDH1A1 (0.49) | POLBALDH1A1CASP3CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098269-A2 | PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. (US) | 2018-05-31 | — | — | WO | disclosed |