Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 1.00 |
| ▸ | ST14 | Q9Y5Y6 | 10/20 | 1.00 |
| ▸ | F2 | P00734 | 9/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 8/20 | 1.00 |
| ▸ | PRSS2 | P07478 | 8/20 | 1.00 |
| ▸ | PRSS3 | P35030 | 8/20 | 1.00 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL850834 | 0.92 | ST14 (1.00) | F10ST14F2PRSS1PRSS2 | |
| SCHEMBL851801 | 0.86 | F10 (1.00) | F10ST14F2PRSS1PRSS2 | |
| SCHEMBL851855 | 0.85 | ST14 (0.73) | F10ST14F2PRSS1PRSS2 | |
| SCHEMBL851552 | 0.83 | ST14 (0.71) | F10ST14F2PRSS1PRSS2 | |
| SCHEMBL850902 | 0.81 | ST14 (0.81) | F10ST14F2PRSS1PRSS2 | |
| SCHEMBL851435 | 0.80 | MRGPRX1 (0.82) | F10ST14F2PRSS1PRSS2 | |
| SCHEMBL851158 | 0.80 | ST14 (0.67) | F10ST14F2PRSS1PRSS2 | |
| SCHEMBL852138 | 0.77 | ST14 (1.00) | F10ST14F2PRSS1PRSS2 | |
| SCHEMBL851310 | 0.77 | ST14 (1.00) | F10ST14F2PRSS1PRSS2 | |
| SCHEMBL851757 | 0.76 | ST14 (0.81) | F10ST14F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2014-07-17 | — | — | US | disclosed |
| US-8722930-B2 | Protease inhibitors | ORION CORPORATION (FI) | 2014-05-13 | — | — | US | disclosed |
| US-20120136002-A1 | PROTEASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-31 | — | — | US | disclosed |
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | F10 152/4885ST14 216/4885F2 112/4885 |
| US-20120136002-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | F10 152/4885ST14 216/4885F2 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.