Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9169241 | 0.87 | TRPA1 (0.46) | TSHRBCHETYRACHETRPA1 | |
| SCHEMBL8518211 | 0.83 | TSHR (0.44) | TSHRGABRA1GABRB2TRPA1ATM | |
| SCHEMBL8519171 | 0.82 | TSHR (0.40) | TSHRATMMAPTMEN1KMT2A | |
| SCHEMBL29860994 | 0.81 | TSHR (0.68) | TSHRGABRA1GABRB2BCHETYR | |
| SCHEMBL296591 | 0.81 | TSHR (0.68) | TSHRGABRA1GABRB2BCHETYR | |
| SCHEMBL7809655 | 0.79 | TSHR (0.65) | TSHRGABRA1GABRB2BCHETYR | |
| Ammonia Solution, Strong SCHEMBL28876892 | 0.79 | TSHR (0.65) | TSHRGABRA1GABRB2BCHETYR | |
| SCHEMBL936321 | 0.77 | TSHR (0.63) | TSHRGABRA1GABRB2BCHETYR | |
| SCHEMBL1238318 | 0.77 | TSHR (0.63) | TSHRGABRA1GABRB2BCHETYR | |
| SCHEMBL836116 | 0.77 | GABRA1 (0.52) | TSHRGABRA1GABRB2TYRTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925691-A | MIXING WITH REFRACTORY AN ALKALINE PHENOL-ALDEHYDE RESIN PRODUCED BY THE COPOLYCONDENSATION OF: A PHENOL, POLYHYDRIC PHENOL, OR ALKYLPHENOL WITH A BISPHENOL AND AN ALDEHYDE COMPOUND; FLOWABILITY AND FILLING PROPERTIES | KAO CORPORATION (JP) | 1999-07-20 | — | — | US | disclosed |
| EP-0606149-A2 | Binder composition for mold and method for producing mold | KAO CORPORATION (JP) | 1994-07-13 | — | — | EP | disclosed |