Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.67 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.67 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.67 |
| ▸ | ST14 | Q9Y5Y6 | 6/20 | 0.67 |
| ▸ | PLG | P00747 | 4/20 | 0.67 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | IL18 | Q14116 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509703 | 1.00 | F2 (0.67) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851253 | 0.88 | F2 (0.52) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL8509807 | 0.82 | DRD2 (0.47) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851416 | 0.82 | DRD2 (0.47) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL8509771 | 0.82 | DRD2 (0.47) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851603 | 0.81 | PTPN2 (0.58) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851407 | 0.80 | F2 (0.54) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL852017 | 0.80 | ST14 (1.00) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL9880184 | 0.80 | ST14 (1.00) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851814 | 0.79 | F2 (0.78) | F2PRSS1PRSS2PRSS3ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |