Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5682532 | 1.00 | SHBG (0.48) | SHBGAKR1C3ESR1ESR2LMNA | |
| SCHEMBL5682603 | 1.00 | SHBG (0.48) | SHBGAKR1C3ESR1ESR2LMNA | |
| SCHEMBL5681898 | 0.85 | SHBG (0.68) | SHBGESR1ESR2LMNACYP2C9 | |
| SCHEMBL5678022 | 0.85 | SHBG (0.68) | SHBGESR1ESR2LMNACYP2C9 | |
| SCHEMBL6258554 | 0.85 | SHBG (0.68) | SHBGESR1ESR2LMNACYP2C9 | |
| SCHEMBL6255675 | 0.85 | SHBG (0.68) | SHBGESR1ESR2LMNACYP2C9 | |
| SCHEMBL4593726 | 0.85 | SHBG (0.68) | SHBGESR1ESR2LMNACYP2C9 | |
| SCHEMBL3357076 | 0.85 | SHBG (0.68) | SHBGESR1ESR2LMNACYP2C9 | |
| SCHEMBL6256154 | 0.85 | SHBG (0.68) | SHBGESR1ESR2LMNACYP2C9 | |
| SCHEMBL14116626 | 0.85 | SHBG (0.68) | SHBGESR1ESR2LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915905-A1 | PROCESS FOR PREPARING 16$g(a)-HYDROXY-ESTRA-1,3,5(10)-TRIENE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004577-A1 | PROCESS FOR PREPARING 16α-HYDROXY-ESTRA-1,3,5(10)-TRIENE DERIVATIVES | SCHERING AG (DE) | 1998-02-05 | — | — | WO | disclosed |
| WO-1998004577-A1 | PROCESS FOR PREPARING 16α-HYDROXY-ESTRA-1,3,5(10)-TRIENE DERIVATIVES | SCHERING AG (DE) | 1998-02-05 | — | — | WO | disclosed |
| WO-1998004577-A1 | PROCESS FOR PREPARING 16α-HYDROXY-ESTRA-1,3,5(10)-TRIENE DERIVATIVES | SCHERING AG (DE) | 1998-02-05 | — | — | WO | disclosed |